FGF1 protein can be used to control blood glucose concentration

FGF1 protein can be used to control blood glucose concentration

Type 2 diabetes can be solved by regular injections of insulin, but a new study shows that a protein called FGF1 may be more effective in solving the problem. The new study found that protein therapy does not only maintain blood sugar, it also eliminates insulin insensitivity, which does not cause side effects.
"Control of blood sugar is our primary treatment for diabetes," said study author Ronald M. Evans, director of the gene expression laboratory at Salk Institute, "and FGF1 is provided in an unexpected way. A new way to control blood sugar." As a chronic disease, diabetes can cause a lot of health problems and cannot be cured. However, it can be controlled through a mixed diet, regular exercise, and treatment. Currently in the market, blood glucose levels are controlled by increasing insulin levels or by restoring genes to restore islet function. But sometimes insulin lowers glucose levels too much, which can lead to life-threatening hypoglycemia and other side effects.
Salk researchers found that mice without FGF1 growth factors rapidly develop diabetes after being given a high-fat diet. To validate their theory, scientists injected FGF1 protein into severe diabetic mice and measured the potential of the protein for metabolism. influences. Scientists have found that blood glucose levels are rapidly dropping to normal. "Many previous studies considered that injection of FGF1 had no effect on healthy mice, however, when we injected into diabetic mice, we saw a significant improvement in glucose." And the protein did not cause even when used in large doses. The side effects of traditional treatments may cause blood glucose levels to drop to dangerous levels. Instead, it keeps the amount of glucose in a safe range. In essence, FGF1 reverses the main symptoms of diabetes.
The research team said that they could not explain the exact mechanism of FGF1 effects, but they said the work would be to use proteins to develop the treatment. "We hope to develop a new generation of FGF1 variants that only affect blood sugar without bringing about cell growth," Evans said. "If we can find the perfect protein, it will be a very effective tool for blood glucose control."

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